Therapy Imaging Probe System

References

+ TIPS Brochure
+ Inline Degasser Brochure

B.I. Raju, C.S. Hall, M.S. Hughes, S.A. Wickline, and G.M. Lanza, “Ultrasound-Mediated Nanoparticle Drug Delivery in an In-Vivo Tumor Model,” J. Acoust. Soc. Am., Vol. 120, No. 5, Pt. 2, November 2006 (Fourth Joint Meeting: ASA and ASJ).

W.T. Shi, M. Boehmer, A. van Wamel, M. Celebi, A.L. Klibanov, C.T. Chin, C. Chlon, M. Emmer, K. Kooiman, N. de Jong, and C.S. Hall, “Ultrasound Therapy with Drug Loaded Microcapsules,” Proceedings of the 2007 IEEE Ultrasonics Symposium, pp. 773-776.

W.T. Shi, M. Böhmer, M. Celebi, A. van Wamel, C.T. Chin, C. Chlon, A.L. Klibanov, and C.S. Hall, "Ultrasound Activated Paclitaxel Delivery in Mice Using a Combined Therapy and Imaging Probe System," Proceedings of the 2008 IEEE Ultrasonics Symposium, pp. 337-340.

E. Svoboda, “10 High-Tech Health Breakthroughs Coming Soon to Your Body – Targeted Delivery”, Popular Mechanics, June 2008 Issue

R. Seip, “TIPS: Site Targeted Delivery with Focused Ultrasound,” Controlled Release Society 2008 Soapbox Session, July 2008.

T.I. Shevchenko, C.T. Chin, and A.L. Klibanov, “Liquid perfluorocarbon droplets: ultrasound-activated enhancers of ultrasound imaging and therapy,” MRgFUS 2008 International Symposium, October 2008.

C.T. Chin, T.I. Shevchenko, B. Verhaagen, and A.L. Klibanov, “Liposome-microbubble pendants allow ultrasound-triggered release of liposome contents,” MRgFUS 2008 International Symposium, October 2008.

A. Ghanem, C. Steingen, F. Brenig, ZY. Bai, C. Hall, C.T. Chin, G. Nickenig, W. Bloch, and K. Tiemann, “Ultrasound-induced stimulation of microbubbles augments and targets myocardial engraftment of mesenchymal stem cells in vivo,”  presented at the American Heart Association Annual Meeting, November 2008, New Orleans.

W.T. Shi, M. Boehmer, M. Celebi, A. van Wamel, C.T. Chin, C. Chlon, A.L. Klibanov, and C.S. Hall, “Ultrasound Activated Drug Delivery with a Preclinical Therapy and Imaging System,” AIUM 2009 Conference, April 2009.

K. Kooiman, M.R. Boehmer, M. Emmer, H.J. Vos, C. Chlon, W.T. Shi, C.S. Hall, S. de Winter, K. Schroeen, M. Versluis, N. de Jong, and A. van Wamel, “Oil-filled polymer mircocapsules for ultrasound-mediated delivery of lipophilic drugs,” Journal of Controller Release 133 (2009), pp. 109-118.

C. Hall, C.T. Chin, K. Tiemann, and A. Ghanem, “Ultrasound enhanced stem cell delivery device and method”, patent application submitted to THE UNITED STATES PATENT AND TRADEMARK OFFICE, September 2008.

Dan Harvey, “Tiny Bubbles,” Radiology Today, Vol. 10, No. 1, p. 16, January 12, 2009.

M.R. Böhmer, A.L. Klibanov, K. Tiemann, C.S. Hall, H. Gruell, and O.C. Steinbach, “Ultrasound triggered image-guided drug delivery,” Eur J Radiol (2009), doi:10.1016/j.ejrad.2009.01.051 (in press).

R. Seip, C.T. Chin, C. Hall, B. Raju, A. Ghanem, and K. Tiemann, “Targeted Ultrasound Mediated Delivery of Nanoparticles: on the development of a new HIFU-based therapy and imaging device,” accepted for publication to the IEEE Transactions on Biomedical Engineering.

C.T. Chin, C. Hall, and A.L. Klibanov, "Tumor treatment using ultrasound cavitation," pending patent application submitted to THE UNITED STATES PATENT AND TRADEMARK OFFICE, April 2009.

A.L. Klibanov, T. Shevchenko, M. Celebi, C. Hall, and C. Chin, "Reduction of blood flow in the tumor vasculature after microbubble destruction by ultrasound," to be presented at the 2009 RSNA conference.

A. Klibanov, T. Shevchenko, B. Kundu, M. Bohmer, R. Seip, B. Raju, C. Chin, "Destruction of microbubbles in the tumor vasculature by image-guided focused ultrasound inhibits tumor growth," to be presented at the 2009 WMIC conference, Montreal, Canada.

"Microbubbles deal drugs," Medical Design, May 2009, pp. 36-37.

A. Ghanem, C. Steingen, F. Brenig, F. Funcke, Z.Y. Bai, C. Hall, C.T. Chin, G. Nickenig, W. Bloch, K.T. Tiemann, "Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarction," Journal of Molecular and Cellular Cardiology (2009), doi:10.1016/j.yjmcc.2009.06.008

Chien Ting Chin, Alexander Ghanem, Zhiyong Bai, Christopher S Hall, Mareike Mühlmeister, Klaus Tiemann, “Ultrasound mediated gene silencing with short-hairpin RNA,” to be presented at the 2009 IEEE Ultrasonics Symposium.

Chien Ting Chin, Talent Shevchenko, Alexander Klibanov, “Arrest of tumor growth and reduction of tumor size in vivo by combination of intravascular microbubbles and ultrasound,” to be presented at the 2009 IEEE Ultrasonics Symposium.

A.L. Klibanov, T. Shevchenko, B. Kundu, R. Seip, B.I. Raju, and C.T. Chin, “Ultrasound contrast media as a therapy for solid tumor: reduction of tumor size as the result of ultrasound treatment of microbubbles in the tumor vasculature,” to be presented at the 2009 CMR, Copenhagen, Denmark.

R. Seip, "Ultrasound Mediated Drug Delivery Technologies for Localized Treatment," presented at the ICUS Bubble Conference, October 22-23, 2009, Chicago, USA.